Histopathological evaluation of pretransplant donor biopsies in expanded criteria donors with high kidney donor profile index: a retrospective observational cohort study

Summary There is no consensus on the allocation of renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) is used without the need for pretransplant donor biopsies (PTDB). We explored whether PTDB based on Remuzzi Score (RS) allows identification of those margin...

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Veröffentlicht in:Transplant international 2017-10, Vol.30 (10), p.975-986
Hauptverfasser: Sánchez‐Escuredo, Ana, Sagasta, Amaia, Revuelta, Ignacio, Rodas, Lida M., Paredes, David, Musquera, Mireia, Diekmann, Fritz, Campistol, Josep M., Solé, Manel, Oppenheimer, Federico
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Sprache:eng
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Zusammenfassung:Summary There is no consensus on the allocation of renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) is used without the need for pretransplant donor biopsies (PTDB). We explored whether PTDB based on Remuzzi Score (RS) allows identification of those marginal kidneys in the highest calculated KDPI risk group (>91%) that appropriate for single transplantation. A retrospective study was conducted of 485 consecutive kidneys procured from a single center and transplanted if the RS was ≤4. We compared 5‐year kidney and patients survival between KDPI groups and between RS 91% calculated KDPI group, there were no differences in graft survival depending on the RS (
ISSN:0934-0874
1432-2277
DOI:10.1111/tri.12966