Effects of Cognitive Leisure Activity on Cognition in Mild Cognitive Impairment: Results of a Randomized Controlled Trial

Abstract Objective To test the hypothesis that a long-term, structured cognitive leisure activity program is more effective than a health education program at reducing the risk of further cognitive decline in older adults with mild cognitive impairment syndrome (MCI), a high risk for dementia. Desig...

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Veröffentlicht in:Journal of the American Medical Directors Association 2017-08, Vol.18 (8), p.686-691
Hauptverfasser: Doi, Takehiko, PhD, PT, Verghese, Joe, MBBS, Makizako, Hyuma, PhD, PT, Tsutsumimoto, Kota, PhD, PT, Hotta, Ryo, PhD, Nakakubo, Sho, MS, Suzuki, Takao, PhD, MD, Shimada, Hiroyuki, PhD, PT
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Sprache:eng
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Zusammenfassung:Abstract Objective To test the hypothesis that a long-term, structured cognitive leisure activity program is more effective than a health education program at reducing the risk of further cognitive decline in older adults with mild cognitive impairment syndrome (MCI), a high risk for dementia. Design A 3-arm, single-blind randomized controlled trial. Setting Community. Participants A total of 201 Japanese adults with MCI (mean age: 76.0 years, 52% women). Interventions Participants were randomized into 1 of 2 cognitive leisure activity programs (60 minutes weekly for 40 weeks): dance (n = 67) and playing musical instruments (n = 67), or a health education control group (n = 67). Measurements Primary outcomes were memory function changes at 40 weeks. Secondary outcomes included changes in Mini-Mental State Examination and nonmemory domain (Trail Making Tests A and B) scores. Results At 40 weeks, the dance group showed improved memory recall scores compared with controls [mean change (SD): dance group 0.73 (1.9) vs controls 0.01 (1.9); P  = .011], whereas the music group did not show an improvement compared with controls ( P  = .123). Both dance [mean change (SD): 0.29 (2.6); P  = .026] and music groups [mean change (SD): 0.46 (2.1); P  = .008] showed improved Mini-Mental State Examination scores compared with controls [mean change (SD): −0.36 (2.3)]. No difference in the nonmemory cognitive tests was observed. Conclusions Long-term cognitive leisure activity programs involving dance or playing musical instruments resulted in improvements in memory and general cognitive function compared with a health education program in older adults with MCI. Trial Registration UMIN-CTR UMIN000014261.
ISSN:1525-8610
1538-9375
DOI:10.1016/j.jamda.2017.02.013