Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation

Highlights • Molecular mutations have impact on outcome after allogeneic stem cell transplantation in myelofibrosis • CALR mutated patients have a significant improved overall survival • ASXL-1 and IDH2 mutated patients have a lower PFS

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Veröffentlicht in:Biology of blood and marrow transplantation 2017-07, Vol.23 (7), p.1095-1101
Hauptverfasser: Kröger, Nicolaus, Panagiota, Victoria, Badbaran, Anita, Zabelina, Tatjana, Triviai, Ioanna, Araujo Cruz, Michelle Maria, Shahswar, Rabia, Ayuk, Francis, Gehlhaar, Marten, Wolschke, Christine, Bollin, Robin, Walter, Carolin, Dugas, Martin, Wiehlmann, Lutz, Lehmann, Ulrich, Koenecke, Christian, Chaturvedi, Anuhar, Alchalby, Haefaa, Stadler, Michael, Eder, Matthias, Christopeit, Max, Göhring, Gudrun, Koenigsmann, Michael, Schlegelberger, Brigitte, Kreipe, Hans-Heinrich, Ganser, Arnold, Stocking, Carol, Fehse, Boris, Thol, Felicitas, Heuser, Michael
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Sprache:eng
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Zusammenfassung:Highlights • Molecular mutations have impact on outcome after allogeneic stem cell transplantation in myelofibrosis • CALR mutated patients have a significant improved overall survival • ASXL-1 and IDH2 mutated patients have a lower PFS
ISSN:1083-8791
1523-6536
DOI:10.1016/j.bbmt.2017.03.034