Minor Steroidal Alkaloids from the Marine Sponge Corticium sp.

Four new steroidal alkaloids, plakinamine G (1), plakinamine H (2), 4α-hydroxydemethylplakinamine B (3), and tetrahydroplakinamine A (4), along with three known compounds, were isolated from the marine sponge Corticium sp. The structures of these metabolites were elucidated largely by 1D and 2D NMR...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2002-08, Vol.65 (8), p.1206-1209
Hauptverfasser:	Borbone, Nicola, De Marino, Simona, Iorizzi, Maria, Zollo, Franco, Debitus, Cecile, Esposito, Giuseppe, Iuvone, Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	4 alpha -hydroxydemethylplakinamine B Alkaloids - chemistry Alkaloids - isolation & purification Alkaloids - pharmacology Animals Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Biological and medical sciences Cells, Cultured - drug effects Chromatography, High Pressure Liquid Corticium Dose-Response Relationship, Drug General pharmacology Glioma Inhibitory Concentration 50 Macrophages - drug effects Marine Medical sciences Mice Molecular Conformation Molecular Structure natural products Nuclear Magnetic Resonance, Biomolecular Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments plakinamine G plakinamine H Porifera - chemistry Rats steroidal alkaloids Steroids - chemistry Steroids - isolation & purification Steroids - pharmacology tetrahydroplakinamine A Vanuatu
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