Diversity in AMPA receptor complexes in the brain

Highlights • AMPAR function depends to a large extend on AMPAR-interacting proteins. • The composition of AMPAR complexes vastly differs across distinct brain regions and developmental stages. • More than 30 AMPAR complex members have been identified so far. • AMPAR complexes comprise proteins with diverse functions. • The better understanding of AMPAR complex diversity recently led to the discovery of a potentially antiepileptic drug.