A new MICA allele, MICA007:07, characterized by cloning and sequencing

Summary A new MICA allelic variant, MICA*007:07, was identified in an individual of Mongol ethnicity in the Inner Mongolia Autonomous Region, northern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. MICA*007...

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Veröffentlicht in:International journal of immunogenetics 2017-06, Vol.44 (3), p.145-147
Hauptverfasser: Wang, W. Y., Tian, W., Wang, F., Zhu, F. M., Wang, P. X., Xing, L. F.
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Sprache:eng
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Zusammenfassung:Summary A new MICA allelic variant, MICA*007:07, was identified in an individual of Mongol ethnicity in the Inner Mongolia Autonomous Region, northern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. MICA*007:07 differs from MICA*007:01 by a synonymous mutation from G to A at the 2nd nucleotide position in exon 2. MICA*007:07 was linked to HLA‐B*27:05.
ISSN:1744-3121
1744-313X
DOI:10.1111/iji.12311