Impact of post‐transplant minimal residual disease on the clinical outcome of pediatric acute leukemia

This retrospective study examined the clinical significance of FCM‐MRD in 36 patients with ALL and 29 patients with AML after their first allogeneic HSCT. Hematological (FCM‐MRD ≥5.0%) and molecular relapse (FCM‐MRD

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Bibliographische Detailangaben
Veröffentlicht in:	Pediatric transplantation 2017-06, Vol.21 (4), p.n/a
Hauptverfasser:	Umeda, Katsutsugu, Iwai, Atsushi, Kawaguchi, Koji, Mikami, Masamitsu, Nodomi, Seishiro, Saida, Satoshi, Hiramatsu, Hidefumi, Heike, Toshio, Ohmori, Katsuyuki, Adachi, Souichi
Format:	Artikel
Sprache:	eng
Schlagworte:	acute leukemia Acute myeloid leukemia Adolescent allogeneic hematopoietic stem cell transplantation Chemotherapy Child Child, Preschool Clinical outcomes Female flow cytometry Follow-Up Studies Hematology Hematopoietic Stem Cell Transplantation Humans Immunology Immunosuppressive agents Infant Infant, Newborn Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - pathology Leukemia, Myeloid, Acute - therapy Male Minimal residual disease Neoplasm, Residual pediatric Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Retrospective Studies Stem cell transplantation Survival Analysis Treatment Outcome
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Zusammenfassung:	This retrospective study examined the clinical significance of FCM‐MRD in 36 patients with ALL and 29 patients with AML after their first allogeneic HSCT. Hematological (FCM‐MRD ≥5.0%) and molecular relapse (FCM‐MRD
ISSN:	1397-3142 1399-3046
DOI:	10.1111/petr.12926