Paediatric systemic lupus erythematosus: insights from translational research
Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focus...
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| Veröffentlicht in: | Rheumatology (Oxford, England) England), 2017-04, Vol.56 (suppl_1), p.i24-i31 |
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| container_issue | suppl_1 |
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| container_title | Rheumatology (Oxford, England) |
| container_volume | 56 |
| creator | Wright, Tracey B Punaro, Marilynn |
| description | Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research. |
| doi_str_mv | 10.1093/rheumatology/kew447 |
| format | Article |
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This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.</description><subject>Adolescent</subject><subject>Age of Onset</subject><subject>Biomarkers</subject><subject>Child</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Interferon Type I - immunology</subject><subject>Lupus Erythematosus, Systemic - drug therapy</subject><subject>Lupus Erythematosus, Systemic - immunology</subject><subject>Lupus Erythematosus, Systemic - physiopathology</subject><subject>Translational Medical Research</subject><issn>1462-0324</issn><issn>1462-0332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkE1Pg0AQhjdGY2v1F5gYjl6wu8wCizfT-JXU6EHPZFlmCwql7iwx_HtpWhtP8x7ej8nD2KXgN4JnMHcV9q32XdOthvkX_kiZHrGpkEkUcoDo-KAjOWFnRJ-c81iAOmWTSEEay1hO2cubxrLW3tUmoIE8tqNo-k1PAbrBV7hdoJ5ug3pN9aryFFjXtYF3ek2N9nW31k3gkFA7U52zE6sbwov9nbGPh_v3xVO4fH18XtwtQwMx92GMUpWikKook0jwxGiTQZpphMymQpZJUZjxQwtgYqPQRoanwFUBqrRlZgXM2PWud-O67x7J521NBptGr7HrKRdKSZFAItVohZ3VuI7Ioc03rm61G3LB8y3H_D_HfMdxTF3tB_qixfKQ-QMHv_cldbw</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Wright, Tracey B</creator><creator>Punaro, Marilynn</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170401</creationdate><title>Paediatric systemic lupus erythematosus: insights from translational research</title><author>Wright, Tracey B ; Punaro, Marilynn</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-5e48d1b48bd62106cac9379ae39f714d6bbc837f33c5c8ef2c07308b38dfd9f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Age of Onset</topic><topic>Biomarkers</topic><topic>Child</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Interferon Type I - immunology</topic><topic>Lupus Erythematosus, Systemic - drug therapy</topic><topic>Lupus Erythematosus, Systemic - immunology</topic><topic>Lupus Erythematosus, Systemic - physiopathology</topic><topic>Translational Medical Research</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wright, Tracey B</creatorcontrib><creatorcontrib>Punaro, Marilynn</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wright, Tracey B</au><au>Punaro, Marilynn</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paediatric systemic lupus erythematosus: insights from translational research</atitle><jtitle>Rheumatology (Oxford, England)</jtitle><addtitle>Rheumatology (Oxford)</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>56</volume><issue>suppl_1</issue><spage>i24</spage><epage>i31</epage><pages>i24-i31</pages><issn>1462-0324</issn><eissn>1462-0332</eissn><abstract>Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. 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| fulltext | fulltext |
| identifier | ISSN: 1462-0324 |
| ispartof | Rheumatology (Oxford, England), 2017-04, Vol.56 (suppl_1), p.i24-i31 |
| issn | 1462-0324 1462-0332 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Adolescent Age of Onset Biomarkers Child Glucocorticoids - therapeutic use Humans Interferon Type I - immunology Lupus Erythematosus, Systemic - drug therapy Lupus Erythematosus, Systemic - immunology Lupus Erythematosus, Systemic - physiopathology Translational Medical Research |
| title | Paediatric systemic lupus erythematosus: insights from translational research |
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