One-pot Synthesis of Novel 2-(Benzofuran-2-yl)-4-Phenylquinoline-3-Carboxylates

One-pot Synthesis of Novel 2-(Benzofuran-2-yl)-4-Phenylquinoline-3-Carboxylates

A facile and efficient synthesis of novel ethyl 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates and the corresponding acids through the one-pot three-step reaction of ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate with a series of salicylaldehydes is described. It allows an efficient an...

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Veröffentlicht in:Journal of chemical research 2017-01, Vol.41 (1), p.45-49
Hauptverfasser: Gao, Wentao, Fu, Xinbo, Zhao, Yanan, Wang, Dongfang
Format: Artikel
Sprache:eng
Schlagworte:
Synthesis
Synthesis (chemistry)
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Zusammenfassung:A facile and efficient synthesis of novel ethyl 2-(benzofuran-2-yl)-4-phenylquinoline-3-carboxylates and the corresponding acids through the one-pot three-step reaction of ethyl 2-(chloromethyl)-4-phenylquinoline-3-carboxylate with a series of salicylaldehydes is described. It allows an efficient and practical access to some 2-(benzofuran-2-yl)quinolines under transition-metal-free conditions.
ISSN:1747-5198
2047-6507
DOI:10.3184/174751917X14839766277170