First report on bio-catalytic N-formylation of amines using ethyl formate
A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also w...
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2017, Vol.53 (15), p.2382-2385 |
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creator | Patre, Rupesh E Mal, Sanjib Nilkanth, Pankaj R Ghorai, Sujit K Deshpande, Sudhindra H El Qacemi, Myriem Smejkal, Tomas Pal, Sitaram Manjunath, Bhanu N |
description | A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also works on a large scale in high yield. |
doi_str_mv | 10.1039/c6cc07679c |
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This method also works on a large scale in high yield.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c6cc07679c</identifier><identifier>PMID: 28174765</identifier><language>eng</language><publisher>England</publisher><subject>Amines ; Effectiveness ; Formates ; Lipase ; Recyclability ; Strategy ; Substrates</subject><ispartof>Chemical communications (Cambridge, England), 2017, Vol.53 (15), p.2382-2385</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-be5da5f34c50587716148d0848cb1d6a5f5cfbef32be60c9fecea30e6100fd6a3</citedby><cites>FETCH-LOGICAL-c386t-be5da5f34c50587716148d0848cb1d6a5f5cfbef32be60c9fecea30e6100fd6a3</cites><orcidid>0000-0001-9834-1724</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28174765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patre, Rupesh E</creatorcontrib><creatorcontrib>Mal, Sanjib</creatorcontrib><creatorcontrib>Nilkanth, Pankaj R</creatorcontrib><creatorcontrib>Ghorai, Sujit K</creatorcontrib><creatorcontrib>Deshpande, Sudhindra H</creatorcontrib><creatorcontrib>El Qacemi, Myriem</creatorcontrib><creatorcontrib>Smejkal, Tomas</creatorcontrib><creatorcontrib>Pal, Sitaram</creatorcontrib><creatorcontrib>Manjunath, Bhanu N</creatorcontrib><title>First report on bio-catalytic N-formylation of amines using ethyl formate</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also works on a large scale in high yield.</description><subject>Amines</subject><subject>Effectiveness</subject><subject>Formates</subject><subject>Lipase</subject><subject>Recyclability</subject><subject>Strategy</subject><subject>Substrates</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqNkD1PwzAURS0EoqWw8ANQRoQUsOPPjCiiUKmCBSS2yHGewSiJi-0O-fekUJh5y33SPbrDQeic4GuCaXljhDFYClmaAzQnVLCcM_V6uPt5mUvK-AydxPiBpyNcHaNZoYhkUvA5Wi1diCkLsPEhZX7IGudzo5PuxuRM9phbH_qx08lNnbeZ7t0AMdtGN7xlkN7HLtsROsEpOrK6i3C2zwV6Wd49Vw_5-ul-Vd2uc0OVSHkDvNXcUmY45kpKIghTLVZMmYa0Yqq4sQ1YWjQgsCktGNAUgyAY26mnC3T5s7sJ_nMLMdW9iwa6Tg_gt7EmSjGCC1bIf6BCFKWYDE3o1Q9qgo8xgK03wfU6jDXB9c5yXYmq-rZcTfDFfnfb9ND-ob9a6Re2znfq</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>Patre, Rupesh E</creator><creator>Mal, Sanjib</creator><creator>Nilkanth, Pankaj R</creator><creator>Ghorai, Sujit K</creator><creator>Deshpande, Sudhindra H</creator><creator>El Qacemi, Myriem</creator><creator>Smejkal, Tomas</creator><creator>Pal, Sitaram</creator><creator>Manjunath, Bhanu N</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0001-9834-1724</orcidid></search><sort><creationdate>2017</creationdate><title>First report on bio-catalytic N-formylation of amines using ethyl formate</title><author>Patre, Rupesh E ; Mal, Sanjib ; Nilkanth, Pankaj R ; Ghorai, Sujit K ; Deshpande, Sudhindra H ; El Qacemi, Myriem ; Smejkal, Tomas ; Pal, Sitaram ; Manjunath, Bhanu N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-be5da5f34c50587716148d0848cb1d6a5f5cfbef32be60c9fecea30e6100fd6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Amines</topic><topic>Effectiveness</topic><topic>Formates</topic><topic>Lipase</topic><topic>Recyclability</topic><topic>Strategy</topic><topic>Substrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patre, Rupesh E</creatorcontrib><creatorcontrib>Mal, Sanjib</creatorcontrib><creatorcontrib>Nilkanth, Pankaj R</creatorcontrib><creatorcontrib>Ghorai, Sujit K</creatorcontrib><creatorcontrib>Deshpande, Sudhindra H</creatorcontrib><creatorcontrib>El Qacemi, Myriem</creatorcontrib><creatorcontrib>Smejkal, Tomas</creatorcontrib><creatorcontrib>Pal, Sitaram</creatorcontrib><creatorcontrib>Manjunath, Bhanu N</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patre, Rupesh E</au><au>Mal, Sanjib</au><au>Nilkanth, Pankaj R</au><au>Ghorai, Sujit K</au><au>Deshpande, Sudhindra H</au><au>El Qacemi, Myriem</au><au>Smejkal, Tomas</au><au>Pal, Sitaram</au><au>Manjunath, Bhanu N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>First report on bio-catalytic N-formylation of amines using ethyl formate</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2017</date><risdate>2017</risdate><volume>53</volume><issue>15</issue><spage>2382</spage><epage>2385</epage><pages>2382-2385</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. 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language | eng |
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Amines Effectiveness Formates Lipase Recyclability Strategy Substrates |
title | First report on bio-catalytic N-formylation of amines using ethyl formate |
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