First report on bio-catalytic N-formylation of amines using ethyl formate

First report on bio-catalytic N-formylation of amines using ethyl formate

A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also w...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2017, Vol.53 (15), p.2382-2385
Hauptverfasser: Patre, Rupesh E, Mal, Sanjib, Nilkanth, Pankaj R, Ghorai, Sujit K, Deshpande, Sudhindra H, El Qacemi, Myriem, Smejkal, Tomas, Pal, Sitaram, Manjunath, Bhanu N
Format: Artikel
Sprache:eng
Schlagworte:
Amines
Effectiveness
Formates
Lipase
Recyclability
Strategy
Substrates
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A bio-catalyzed N-formylation reaction of different amines has been developed using ethyl formate as a formylating agent. This protocol provides a facile and convenient strategy featuring mild reaction conditions, high efficacy, a broad substrate scope and recyclability of lipase. This method also works on a large scale in high yield.
ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc07679c