Vitamin D deficiency is associated with digital ulcer but not with atherosclerosis or arterial stiffness in patients with systemic sclerosis: a pilot study

The objective of this study was to investigate the association of vitamin D deficiency with digital ulcers (DUs) that result from microvasculopathy, carotid intima-media thickness (CIMT) as surrogate markers of atherosclerosis, and brachial-ankle pulse wave velocity (baPWV) representing arterial sti...

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Veröffentlicht in:	Clinical rheumatology 2017-06, Vol.36 (6), p.1325-1333
Hauptverfasser:	Park, Eun-Kyoung, Park, Ji-Heh, Kweon, Seong-Min, Kim, Geun-Tae, Lee, Seung-Geun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ankle Arteriosclerosis Atherosclerosis Atherosclerosis - blood Atherosclerosis - diagnostic imaging Atherosclerosis - etiology Carotid Intima-Media Thickness Case-Control Studies Cross-Sectional Studies Female Humans Medicine Medicine & Public Health Microvasculature Middle Aged Original Article Pilot Projects Pulse Wave Analysis Rheumatology Scleroderma Scleroderma, Systemic - blood Scleroderma, Systemic - complications Scleroderma, Systemic - diagnostic imaging Skin Ulcer - blood Skin Ulcer - etiology Systemic sclerosis Ulcers Ultrasound Vascular Stiffness Velocity Vitamin D Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D Deficiency - complications Vitamin deficiency
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Zusammenfassung:	The objective of this study was to investigate the association of vitamin D deficiency with digital ulcers (DUs) that result from microvasculopathy, carotid intima-media thickness (CIMT) as surrogate markers of atherosclerosis, and brachial-ankle pulse wave velocity (baPWV) representing arterial stiffness in patients with systemic sclerosis (SSc). In this cross-sectional study, 40 female SSc patients and 80 healthy controls matched for sex, age, and blood sampling season were recruited. Vitamin D deficiency was defined as serum 25-OHD levels
ISSN:	0770-3198 1434-9949
DOI:	10.1007/s10067-017-3622-9