‘Mendelian randomization’: an approach for exploring causal relations in epidemiology

Abstract Objectives To assess the current status of Mendelian randomization (MR) approach in effectively influencing the observational epidemiology for examining causal relationships. Methods Narrative review on studies related to principle, strengths, limitations, and achievements of MR approach. R...

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Veröffentlicht in:	Public health (London) 2017-04, Vol.145, p.113-119
Hauptverfasser:	Gupta, V, Walia, G.K, Sachdeva, M.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Causality Chronic illnesses Clinical trials Epidemiologic Methods Epidemiology Genetic diversity Genetic variance Genetic Variation Genome-wide association studies Genome-Wide Association Study Genomes Humans India Infectious Disease Internal Medicine Mendelian randomization Mendelian Randomization Analysis - methods Observational studies Random Allocation Randomization Randomized Controlled Trials as Topic Variants
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