Performance of Serological and Molecular Tests within Acute HIV Infection

Highlights • Seroconversion specimens from FEM-PrEP trial are used for the evaluation of three fourth generation simple rapid tests (SRT). • SD-Bioline HIVAg/Ab combo test is the most sensitive SRT in detecting early infections.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical virology 2017-08, Vol.93, p.81-84
Hauptverfasser:	Fransen, Katrien, de Baetselier, Irith, Rammutla, Elizabeth, Ahmed, Khatija, Owino, Frederick, Agingu, Walter, Venter, Gustav, Deese, Jen, Van Damme, Lut, Crucitti, Tania
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Early Diagnosis Early HIV diagnosis HIV Antibodies - blood HIV Antigens - immunology HIV Infections - diagnosis HIV Infections - immunology HIV Infections - virology HIV Seropositivity HIV-1 - genetics HIV-1 - immunology Humans Infectious Disease Molecular Diagnostic Techniques Nucleic Acid Amplification Techniques RNA, Viral - genetics Sensitivity and Specificity Simple rapid tests
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Beschreibung
Zusammenfassung:	Highlights • Seroconversion specimens from FEM-PrEP trial are used for the evaluation of three fourth generation simple rapid tests (SRT). • SD-Bioline HIVAg/Ab combo test is the most sensitive SRT in detecting early infections.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2017.03.010