Clonal analysis as a prognostic factor in multiple oral squamous cell carcinoma

Highlights • mtDNA analysis is a molecular method to evaluate the clonality of secondary tumors. • mtDNA analysis differentiated 23 OSCCs in 7 LRs, 4 SPTs and 12 SFTs. • SFTs showed a better survival rate with respect to LRs and SPTs. • mtDNA analysis may influence the prognosis and treatment in mul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2017-04, Vol.67, p.131-137
Hauptverfasser:	Gissi, D.B, Tarsitano, A, Leonardi, E, Gabusi, A, Neri, F, Marchetti, C, Montebugnoli, L, Foschini, M.P, Morandi, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Female Hematology, Oncology and Palliative Medicine Humans Local recurrence Male Middle Aged Mouth Neoplasms - pathology Mouth Neoplasms - therapy mtDNA Oral squamous cell carcinoma Otolaryngology Prognosis Second field tumour Second primary tumour Survival Rate Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • mtDNA analysis is a molecular method to evaluate the clonality of secondary tumors. • mtDNA analysis differentiated 23 OSCCs in 7 LRs, 4 SPTs and 12 SFTs. • SFTs showed a better survival rate with respect to LRs and SPTs. • mtDNA analysis may influence the prognosis and treatment in multiple OSCCs.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2017.02.017