Mechanism of cinnamaldehyde sensitization

Mechanism of cinnamaldehyde sensitization

The skin sensitization of cinnamaldehyde is probably initialed by the reaction of cinnamaldehyde with ɛ‐amino groups on protein side chains. α‐Substituted cinnamaldehydes, which are known nottobe skin sensitizers, react very slowly or not at all with amines in comparison with cinnamaldehyde.

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Bibliographische Detailangaben
Veröffentlicht in:Contact dermatitis 1977-02, Vol.3 (1), p.16-18
Hauptverfasser: Majeti, Vimala A., Suskind, Raymond R.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cinnamaldehyde
Dermatitis, Contact - etiology
Guinea Pigs
Humans
Hypersensitivity - immunology
mechanism
Perfume - adverse effects
Schiff base
Skin - immunology
skin sensitization
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Beschreibung
Zusammenfassung:The skin sensitization of cinnamaldehyde is probably initialed by the reaction of cinnamaldehyde with ɛ‐amino groups on protein side chains. α‐Substituted cinnamaldehydes, which are known nottobe skin sensitizers, react very slowly or not at all with amines in comparison with cinnamaldehyde.
ISSN:0105-1873
1600-0536
DOI:10.1111/j.1600-0536.1977.tb03581.x