Impact of Clostridium difficile infection in patients hospitalized with acute pancreatitis- a population based cohort study

Impact of Clostridium difficile infection in patients hospitalized with acute pancreatitis- a population based cohort study

A multivariate logistic regression analysis adjusting for patient demographics, hospital characteristics, comorbidities and AP etiology demonstrated that CDI was associated with increased mortality [adjusted odds ratio (aOR) 3.15, 95% CI 2.78-3.57, p < 0.001], LOS [adjusted regression coefficient...

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Veröffentlicht in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2017-03, Vol.17 (2), p.201-202
Hauptverfasser: Trikudanathan, Guru, MD, Munigala, Satish, MBBS, MPH
Format: Artikel
Sprache:eng
Schlagworte:
Acute pancreatitis
Antibiotics
C diff
Clostridium difficile
Cohort analysis
Demography
Endocrinology & Metabolism
Etiology
Gastroenterology and Hepatology
Infections
Mortality
Nationwide inpatient database
Pancreatitis
Patients
Population studies
Population-based studies
Trends
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Zusammenfassung:A multivariate logistic regression analysis adjusting for patient demographics, hospital characteristics, comorbidities and AP etiology demonstrated that CDI was associated with increased mortality [adjusted odds ratio (aOR) 3.15, 95% CI 2.78-3.57, p < 0.001], LOS [adjusted regression coefficient (aRC) 8.85, 95%CI 8.62-9.08, p < 0.001] and higher hospital charges (aRC $48,725, 95%CI $47,024-$50,425, p < 0.001). Indiscriminate use of antibiotics and poor compliance to the guidelines was reported in a recent audit [5]. Besides encouraging...
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2017.02.012