PEGylated recombinant L-asparaginase from Erwinia carotovora: Production, properties, and potential applications

N-hydroxysuccinimide ester of monomethoxy polyethylene glycol hemisuccinate was synthesized. It acylated amino groups in a molecule of recombinant L-asparaginase from Erwinia carotovora . A method of L-asparaginase modification by the obtained activated polyethylene glycol derivative was developed....

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Applied biochemistry and microbiology 2017-03, Vol.53 (2), p.165-172
Hauptverfasser:	Melik-Nubarov, N. S., Grozdova, I. D., Lomakina, G. Yu, Pokrovskaya, M. V., Pokrovski, V. S., Aleksandrova, S. S., Abakumova, O. Yu, Podobed, O. V., Grishin, D. V., Sokolov, N. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Cancer therapies Enzymes Erwinia carotovora Life Sciences Medical Microbiology Microbiology Polyethylene glycol
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!