Set up of cutoff thresholds for kinship determination using SNP loci
Highlights • Discriminatory power of 80 SNP loci was suitable for parent-child relationships. • Applying 136 SNP loci applied to analysis was sufficient for full-sibling determination with the highest accuracy and sensitivity. • Indistinguishable full-sibling relationships with only 15 STR data were...
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Veröffentlicht in: | Forensic science international : genetics 2017-07, Vol.29, p.1-8 |
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container_title | Forensic science international : genetics |
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creator | Cho, Sohee Shin, Eun Soon Yu, Hyung Jin Lee, Ji Hyun Seo, Hee Jin Kim, Moon Young Lee, Soong Deok |
description | Highlights • Discriminatory power of 80 SNP loci was suitable for parent-child relationships. • Applying 136 SNP loci applied to analysis was sufficient for full-sibling determination with the highest accuracy and sensitivity. • Indistinguishable full-sibling relationships with only 15 STR data were successfully resolved by SNP data with significant difference in the median value. |
doi_str_mv | 10.1016/j.fsigen.2017.03.009 |
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source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
subjects | Asian Continental Ancestry Group - genetics Forensic Genetics Full-sibling Humans Kinship Likelihood Functions Likelihood ratio Linkage Disequilibrium Pathology Pedigree Polymorphism, Single Nucleotide Republic of Korea Single nucleotide polymorphism Uncle-nephew |
title | Set up of cutoff thresholds for kinship determination using SNP loci |
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