Synthesis of novel C-9 carbon substituted derivatives of artemisinin

Several artemisinin derivatives carrying several groups (alkyl, hydroxyalkyl, allyl or azide) at position 9 have been synthesized starting from artemisinin via enolate formation and subsequent reaction with appropriate electrophiles. [Display omitted] Several artemisinin derivatives carrying several...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bioorganic & medicinal chemistry 2017-11, Vol.25 (22), p.6098-6101
Hauptverfasser:	Meyer, Daniel, Smeilus, Toni, Pliatsika, Dimanthi, Mousavizadeh, Farnoush, Giannis, Athanassios
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes - chemistry Anticancer Antimalarial Antimalarials - chemical synthesis Antimalarials - chemistry Antimalarials - pharmacology Artemisinin Artemisinins - chemical synthesis Artemisinins - chemistry Artemisinins - pharmacology Carbon - chemistry Plasmodium falciparum - drug effects Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!