Odontoclastogenesis of mouse papilla‐derived MDPC‐23 cells induced by lipopolysaccharide

Aim To investigate the role of Lipopolysaccharide (LPS) in the odontoclast differentiation of MDPC‐23 cells. It was hypothesized that MDPC‐23 odontoblast‐like cells may function as odontoclasts under the influence of LPS. Methodology MDPC‐23 cells were cultured in the presence of 0.1 or 1 μg mL−1 LP...

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Veröffentlicht in:	International endodontic journal 2018-02, Vol.51 (S2), p.e115-e124
Hauptverfasser:	Li, C., Qi, W. T., Jiang, H. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cathepsin K Cell Differentiation - drug effects Cell Line Cell Proliferation - drug effects Dental Papilla - cytology Dental Papilla - drug effects Dental Papilla - metabolism Dentistry Endodontics Enzyme-Linked Immunosorbent Assay lipopolysaccharide Lipopolysaccharides Lipopolysaccharides - pharmacology Mice Microscopy, Confocal odontoclast Odontoclasts Odontogenesis - drug effects osteoclast Osteoclasts - drug effects Osteoclasts - metabolism Rac1 protein RANKL‐RANK signalling pathway Reactive Oxygen Species - metabolism Rodents Root resorption Signal transduction Statistical analysis TRAF6 protein TRANCE protein Western blotting
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