Tp-e interval and Tp-e/QT ratio before and after catheter ablation in patients with premature ventricular complexes

Tp-e/QT ratio is a novel marker of ventricular repolarization. The aim of the study is to evaluate the Tp-e interval and Tp-e/QT ratio before and after radiofrequency ablation (RFA) for patients with frequent premature ventricular complexes (PVCs). The study included 151 consecutive patients who underwent RFA for treatment of symptomatic frequent PVCs. Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio (all p < 0.001) were significantly different before and after RFA. After the procedure, mean left ventricular ejection fraction of the population were significantly increased than before RFA (p < 0.001). There was a significant correlation between preprocedural Tp-e/QTc ratio and PVC burden in patients (p = 0.023). Our study shows that PVCs may have a negative effect on ventricular repolarization.