Compressive fluorescence imaging using a multi-core fiber and spatially dependent scattering

We demonstrate imaging using a multi-core fiber with a scattering distal tip and compressed sensing signal acquisition. We illuminate objects with randomly structured speckle patterns generated by a coherent light source separately coupled through each fiber core to a ground glass diffuser at the distal end. Using the characterized speckle patterns and the total light collected from the object, we computationally recover pixelation-free object images with up to a seven times higher space-bandwidth product than the number of cores. The proposed imaging system is insensitive to bending of the fiber and extremely compact, making it suitable for minimally invasive endomicroscopy.