Statistical Comparison of Mass Spectra for Identification of Amphetamine-Type Stimulants

Statistical Comparison of Mass Spectra for Identification of Amphetamine-Type Stimulants

Highlights • Unequal variance t-test used to compare two mass spectra at every m/z value. • Amphetamine-type stimulants associated to reference standard at 99.9% confidence level. • Distinction from other reference standards at 99.9% and 99.0% confidence level. • Random-match probability (RMP) calcu...

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Veröffentlicht in:Forensic science international 2017-01, Vol.270, p.111-120
Hauptverfasser: Bodnar Willard, Melissa A, McGuffin, Victoria L, Smith, Ruth Waddell
Format: Artikel
Sprache:eng
Schlagworte:
Amphetamine-type stimulants
Amphetamines
Bayesian analysis
Confidence intervals
Controlled substance identification
Discrimination
Forensic sciences
Fragmentation
Gas chromatography–mass spectrometry
Hypotheses
Identification
Laboratories
Mass spectral comparison
Methamphetamine
Pathology
Probability
Samples
Spectra
Statistical analysis
Statistical methods
Stimulants
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Beschreibung
Zusammenfassung:Highlights • Unequal variance t-test used to compare two mass spectra at every m/z value. • Amphetamine-type stimulants associated to reference standard at 99.9% confidence level. • Distinction from other reference standards at 99.9% and 99.0% confidence level. • Random-match probability (RMP) calculated for statistically equivalent spectra. • Number of discriminating ions determined for statistically distinct spectra
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2016.11.013