Nanoparticle release from dental composites

Dental composites typically contain high amounts (up to 60vol.%) of nanosized filler particles. There is a current concern that dental personnel (and patients) may inhale nanosized dust particles (106cm−3). The median diameter of airborne composite dust varied between 38 and 70nm. Electron microscop...

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Veröffentlicht in:Acta biomaterialia 2014-01, Vol.10 (1), p.365-374
Hauptverfasser: Van Landuyt, K.L., Hellack, B., Van Meerbeek, B., Peumans, M., Hoet, P., Wiemann, M., Kuhlbusch, T.A.J., Asbach, C.
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Sprache:eng
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Zusammenfassung:Dental composites typically contain high amounts (up to 60vol.%) of nanosized filler particles. There is a current concern that dental personnel (and patients) may inhale nanosized dust particles (106cm−3). The median diameter of airborne composite dust varied between 38 and 70nm. Electron microscopic and energy dispersive X-ray analysis confirmed that the airborne particles originated from the composite, and revealed that the dust particles consisted of filler particles or resin or both. Though composite dust exhibited no significant oxidative reactivity, more toxicological research is needed. To conclude, on manipulation with the bur, dental composites release high concentrations of nanoparticles that may enter deeply into the lungs.
ISSN:1742-7061
1878-7568
DOI:10.1016/j.actbio.2013.09.044