Hemodynamic improvement and removal of autoantibodies against β 1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy

Hemodynamic improvement and removal of autoantibodies against β 1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy

The removal of β 1-adrenergic receptor (β 1AR) autoantibodies by immunoadsorption (IA) has been proposed as a potential mechanism for the improvement of the left ventricular function in dilated cardiomyopathy (DCM). In the present study, the possible association between removal of the autoantibodies...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of autoimmunity 2003-06, Vol.20 (4), p.345-350
Hauptverfasser: Mobini, Reza, Staudt, Alexander, Felix, Stephan B., Baumann, Gert, Wallukat, Gert, Deinum, Johanna, Svensson, Helen, Hjalmarson, Åke, Fu, Michael
Format: Artikel
Sprache:eng
Schlagworte:
Autoantibodies
Immunoadsorption
β 1-Adrenergic receptor
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The removal of β 1-adrenergic receptor (β 1AR) autoantibodies by immunoadsorption (IA) has been proposed as a potential mechanism for the improvement of the left ventricular function in dilated cardiomyopathy (DCM). In the present study, the possible association between removal of the autoantibodies against the human β 1AR with the hemodynamic improvement induced by IA was investigated. IA was performed in 22 DCM patients ( n=22; NYHA III–IV, EF
ISSN:0896-8411
1095-9157
DOI:10.1016/S0896-8411(03)00042-8