Truncating Titin ( TTN) Variants in Chemotherapy-Induced Cardiomyopathy

Highlights • Truncating titin variants are found in chemotherapy-induced cardiomyopathy • Phenotypic expression after chemotherapy illustrates a second-hit like phenomenon • Genetic testing prior to chemotherapy may improve risk stratification

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cardiac failure 2017-06, Vol.23 (6), p.476-479
Hauptverfasser:	Linschoten, M., BSc, Teske, A.J., MD, PhD, Baas, A.F., MD, PhD, Vink, A., MD, PhD, Dooijes, D., PhD, Baars, H.F., MD, Asselbergs, F.W., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Agents - adverse effects Breast Neoplasms - diagnostic imaging Breast Neoplasms - drug therapy Breast Neoplasms - genetics Carcinoma, Ductal - diagnostic imaging Carcinoma, Ductal - drug therapy Carcinoma, Ductal - genetics Cardiomyopathies - chemically induced Cardiomyopathies - diagnostic imaging Cardiomyopathies - genetics Cardiotoxicity Cardiovascular chemotherapy Connectin - genetics Fatal Outcome Female Genetic Variation - genetics genetics heart failure Humans Middle Aged
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Truncating titin variants are found in chemotherapy-induced cardiomyopathy • Phenotypic expression after chemotherapy illustrates a second-hit like phenomenon • Genetic testing prior to chemotherapy may improve risk stratification
ISSN:	1071-9164 1532-8414
DOI:	10.1016/j.cardfail.2017.03.003