A proposal for standardized grading of chronic changes in native kidney biopsy specimens

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial...

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Veröffentlicht in:	Kidney international 2017-04, Vol.91 (4), p.787-789
Hauptverfasser:	Sethi, Sanjeev, D’Agati, Vivette D., Nast, Cynthia C., Fogo, Agnes B., De Vriese, An S., Markowitz, Glen S., Glassock, Richard J., Fervenza, Fernando C., Seshan, Surya V., Rule, Andrew, Racusen, Lorraine C., Radhakrishnan, Jai, Winearls, Christopher G., Appel, Gerald B., Bajema, Ingeborg M., Chang, Anthony, Colvin, Robert B., Cook, H. Terence, Hariharan, Sundaram, Herrera Hernandez, Loren P., Kambham, Neeraja, Mengel, Michael, Nath, Karl A., Rennke, Helmut G., Ronco, Pierre, Rovin, Brad H., Haas, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	arteriosclerosis Biopsy - standards Disease Progression glomerulosclerosis Humans interstitial fibrosis Kidney - pathology native kidney biopsy Predictive Value of Tests Prognosis Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - pathology Renal Insufficiency, Chronic - therapy Severity of Illness Index Terminology as Topic tubular atrophy
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Beschreibung
Zusammenfassung:	Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.
ISSN:	0085-2538 1523-1755
DOI:	10.1016/j.kint.2017.01.002