Co-circulating serotypes in a dengue fever outbreak: differential hematological profiles and phylogenetic relationships among viruses

Highlights • Dengue virus serotypes 1 (DENV1) and 3 (DENV3) co-circulated in Marilia during 2007 • Hematological profiles of patients infected by different serotypes were similar • Percentage of atypical lymphocytes could be associated to less platelets in DENV1 • Percentage of atypical lymphocytes...

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Veröffentlicht in:	Journal of clinical virology 2017-05, Vol.90, p.7-13
Hauptverfasser:	Carmo, Andreia Moreira dos Santos, Suzuki, Rodrigo Buzinaro, Cabral, Aline Diniz, Costa, Renata Torres da, Massari, Gabriela Pena, Riquena, Michele Marcondes, Fracasso, Helio Augusto Alves, Eterovic, Andre, Marcili, Arlei, Sperança, Márcia Aparecida
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Allergy and Immunology Blood Cells - pathology Brazil - epidemiology Child Cluster Analysis dengue Dengue - epidemiology Dengue - virology Dengue Virus - classification Dengue Virus - genetics Dengue Virus - isolation & purification Disease Outbreaks Female genotype sequence analysis Genotyping Techniques hematological profile Humans Infectious Disease Male Middle Aged Molecular Epidemiology pattern of dengue outbreak Phylogeny Polymerase Chain Reaction Sequence Analysis, DNA Sequence Homology Serogroup Young Adult
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Zusammenfassung:	Highlights • Dengue virus serotypes 1 (DENV1) and 3 (DENV3) co-circulated in Marilia during 2007 • Hematological profiles of patients infected by different serotypes were similar • Percentage of atypical lymphocytes could be associated to less platelets in DENV1 • Percentage of atypical lymphocytes could be associated to severe leucopenia in DENV3 • Apparently, DENV1 was introduced into Marília from northern Brazil
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2017.03.001