Body mass index, fat free mass, uric acid, and renal function as blood pressure levels determinants in young adults

Aim We assessed some major determinants of blood pressure (BP) in young adulthood to plan a lifestyle changes policy Methods A cross sectional survey was held, involving 2373 high school people (age 18–21), measuring BP, body mass index (BMI), waist circumference (WCirc), fat free mass (FFM); alcoho...

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Veröffentlicht in:Nephrology (Carlton, Vic.) Vic.), 2017-04, Vol.22 (4), p.279-285
Hauptverfasser: Sidoti, Antonino, Nigrelli, Santi, Rosati, Alberto, Bigazzi, Roberto, Caprioli, Raffaele, Fanelli, Roberto, Acconcia, Pasqualina, Borracelli, Donella, Biagioli, Marina, Angelini, Daniela, Parrini, Manuela, Tonelli, Luigi, Tosi, Pierluigi, Manzoni, Diego
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Sprache:eng
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Zusammenfassung:Aim We assessed some major determinants of blood pressure (BP) in young adulthood to plan a lifestyle changes policy Methods A cross sectional survey was held, involving 2373 high school people (age 18–21), measuring BP, body mass index (BMI), waist circumference (WCirc), fat free mass (FFM); alcohol and smoking habits were evaluated by a questionnaire. In a subset of this population (n = 60) uric acid (UA), estimated glomerular filtration rate (eGFR) were also evaluated. Results Smoking and not alcohol was correlated to systolic blood pressure (SBP) through quartiles (31.7%, 39.1%, 46.5%, 45.5%). Systolic BP was significantly correlated with FFM in the whole population (r = 0.51) as well as in SBP quartiles (r = 0.243, 0.138, 0.118, 0.204). FFM‐SBP cluster analysis gave two centroids corresponding to sexes; females n = 998; coordinates (116.4 mmHg, 38.9 kg) and males n = 1068; coordinates (131.3 mmHg, 56.7 kg). In the n = 60 substudy a multiple linear regression model (multiple R = 0.741) with SBP as dependent variable and UA, FFM, BMI, eGFR as explicative ones, only UA (β coefficent = 0.363, partial r = 0.240, P 
ISSN:1320-5358
1440-1797
DOI:10.1111/nep.12763