Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Combination Treatment in Patients With HIV/HCV Coinfection: Results of an Italian Compassionate Use Program

Patients coinfected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are at high risk of liver disease progression. We report a favorable safety profile and SVR12 rates of 96.7% among HIV/HCV coinfected patients participating in an Italian compassionate-use program of ombitasvir/p...

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Veröffentlicht in:Clinical infectious diseases 2017-03, Vol.64 (5), p.680-683
Hauptverfasser: Andreoni, Massimo, Teti, Elisabetta, Antinori, Andrea, Milazzoi, Laura, Sollima, Savatore, Rizzardini, Giuliano, Di Biagio, Antonio, Saracino, Annalisa, Bruno, Raffaele, Borghi, Vanni, De Luca, Andrea, Cattelan, Annamaria, Hasson, Hamid, Taliani, Gloria, Monforte, Antonella D'Arminio, Mastroianni, Claudio Maria, Di Perri, Giovanni, Bigoni, Sara, Puoti, Massimo, Spinetti, Angiola, Gori, Andrea, Boffa, Nicola, Cacopardo, Bruno, Giacometti, Andrea, Parruti, Giustino, Vullo, Vincenzo, Chirianni, Antonio, Pennica, Alfredo, Pasquazzi, Caterina, Segala, Daniela, Sarmati, Loredana
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Sprache:eng
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Zusammenfassung:Patients coinfected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are at high risk of liver disease progression. We report a favorable safety profile and SVR12 rates of 96.7% among HIV/HCV coinfected patients participating in an Italian compassionate-use program of ombitasvir/paritaprevir/ritonavir + dasabuvir (OBV/PTV/r + DSV) ± ribavirin (RBV).
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciw846