Effects of aspirin on small-cell lung cancer mortality and metastatic presentation

Highlights • Aspirin has been shown to reduce cancer incidence and mortality, including lung cancer. • Data on the effects of aspirin on small-cell lung cancer (SCLC) are sparse, and conflicting. • We have shown in multivariate analysis of a large cohort of patients with SCLC that aspirin does not i...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2017-04, Vol.106, p.67-69
1. Verfasser:	Maddison, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - pharmacology Aspirin Aspirin - administration & dosage Aspirin - pharmacology Aspirin - therapeutic use Cyclooxygenase 2 - metabolism Female Hematology, Oncology and Palliative Medicine Humans Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Lung Neoplasms - mortality Male Middle Aged Neoplasm Metastasis - drug therapy Neoplasm Metastasis - pathology Neoplasm Staging Observational Prospective Prospective Studies Pulmonary/Respiratory Small Cell Lung Carcinoma - diagnosis Small Cell Lung Carcinoma - drug therapy Small Cell Lung Carcinoma - mortality Small-cell lung cancer Survival Survival Analysis
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Beschreibung
Zusammenfassung:	Highlights • Aspirin has been shown to reduce cancer incidence and mortality, including lung cancer. • Data on the effects of aspirin on small-cell lung cancer (SCLC) are sparse, and conflicting. • We have shown in multivariate analysis of a large cohort of patients with SCLC that aspirin does not improve cancer survival.
ISSN:	0169-5002 1872-8332
DOI:	10.1016/j.lungcan.2017.01.018