The Road to Elucidating the Mechanism of Manganese-Bilirubin–Induced Cholestasis

The article highlighted in this issue is “Synergistic Role of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Cholesterol 7α-Hydroxylase in the Pathogenesis of Manganese-Bilirubin–Induced Cholestasis in Rats,” by Marie-Yvonne Akoume, Shahid Perwaiz, Ibrahim M. Yousef, and Gabriel L. Plaa (pp. 33...

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Veröffentlicht in:	Toxicological sciences 2003-06, Vol.73 (2), p.216-219
1. Verfasser:	GOERING, Peter L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bilirubin - metabolism Bilirubin - pharmacology Biological and medical sciences Cholestasis, Intrahepatic - chemically induced Cholestasis, Intrahepatic - metabolism Cholesterol - metabolism Disease Models, Animal Drug Interactions Gastroenterology. Liver. Pancreas. Abdomen Humans Hydroxymethylglutaryl CoA Reductases - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Manganese - metabolism Manganese - pharmacology Medical sciences Other diseases. Semiology Rats
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Zusammenfassung:	The article highlighted in this issue is “Synergistic Role of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Cholesterol 7α-Hydroxylase in the Pathogenesis of Manganese-Bilirubin–Induced Cholestasis in Rats,” by Marie-Yvonne Akoume, Shahid Perwaiz, Ibrahim M. Yousef, and Gabriel L. Plaa (pp. 331–338).
ISSN:	1096-6080 1096-0929 1096-0929
DOI:	10.1093/toxsci/kfg112