Anthropological analysis of Tunisian populations as inferred from HLA class I and class II genetic diversity: a meta-analysis

Highlights • Except for Berbers of Djerba, all the Tunisian populations are closely related to one another. • The Tunisian populations are very close to North Africans and Iberians but not to Eastern Mediterraneans including the Arabs (Lebanese, Syrians, and Palestinians). • Berbers of Djerba Island...

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Veröffentlicht in:	Immunology letters 2017-05, Vol.185, p.12-26
Hauptverfasser:	Hajjej, Abdelhafidh, Almawi, Wassim Y, Hattab, Lasmar, Hmida, Slama
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Anthropology, Medical Berbers Gene Flow Gene Frequency Genetics, Population Genotype HLA Antigens - genetics HLA polymorphism HLA-A Antigens - genetics HLA-B Antigens - genetics HLA-DQ beta-Chains - genetics HLA-DRB1 Chains - genetics Humans Linkage Disequilibrium Mediterranean Phylogeny Polymorphism, Genetic Tunisia Tunisian
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Beschreibung
Zusammenfassung:	Highlights • Except for Berbers of Djerba, all the Tunisian populations are closely related to one another. • The Tunisian populations are very close to North Africans and Iberians but not to Eastern Mediterraneans including the Arabs (Lebanese, Syrians, and Palestinians). • Berbers of Djerba Island are close to Eastern Mediterraneans. • The contribution of Arabs and Blacks to genetic pool of Tunisians was probably low.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2017.02.014