The local administration of parathyroid hormone encourages the healing of bone defects in the rat calvaria: micro-computed tomography, histological and histomorphometric evaluation
Highlights • The local administration of PTH on bone healing in rat bone defects was evaluated. • Micro-CT, histological and histomorphometric analysis were performed. • At 15 days post-surgery, PTH Group exhibited higher percentage of bone formation. • The results suggest that PTH encouraged the in...
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| Veröffentlicht in: | Archives of oral biology 2017-07, Vol.79, p.14-19 |
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| container_title | Archives of oral biology |
| container_volume | 79 |
| creator | Auersvald, Caroline Moreira Santos, Felipe Rychuv Nakano, Mayara Mytie Leoni, Graziela Bianchi de Sousa Neto, Manoel Damião Scariot, Rafaela Giovanini, Allan Fernando Deliberador, Tatiana Miranda |
| description | Highlights • The local administration of PTH on bone healing in rat bone defects was evaluated. • Micro-CT, histological and histomorphometric analysis were performed. • At 15 days post-surgery, PTH Group exhibited higher percentage of bone formation. • The results suggest that PTH encouraged the initial bone healing in bone defects. |
| doi_str_mv | 10.1016/j.archoralbio.2017.02.016 |
| format | Article |
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Santos, Felipe Rychuv ; Nakano, Mayara Mytie ; Leoni, Graziela Bianchi ; de Sousa Neto, Manoel Damião ; Scariot, Rafaela ; Giovanini, Allan Fernando ; Deliberador, Tatiana Miranda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-b81bc70096a66ef56b75aeec7ca6c2324bbf12e6a8f6f4e464e8b52c2c95b4f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Advanced Basic Science</topic><topic>Animals</topic><topic>Bone regeneration</topic><topic>Bone Regeneration - drug effects</topic><topic>Calvaria</topic><topic>Cattle</topic><topic>Collagen - pharmacology</topic><topic>Dentistry</topic><topic>Male</topic><topic>Micro-CT</topic><topic>Osteogenesis - drug effects</topic><topic>Parathyroid hormone</topic><topic>Parathyroid Hormone - administration & dosage</topic><topic>Parathyroid Hormone - pharmacology</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Skull - diagnostic imaging</topic><topic>Skull - drug effects</topic><topic>Skull - pathology</topic><topic>Skull - surgery</topic><topic>Time Factors</topic><topic>Wound Healing - drug effects</topic><topic>X-Ray Microtomography - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Auersvald, Caroline Moreira</creatorcontrib><creatorcontrib>Santos, Felipe Rychuv</creatorcontrib><creatorcontrib>Nakano, Mayara Mytie</creatorcontrib><creatorcontrib>Leoni, Graziela Bianchi</creatorcontrib><creatorcontrib>de Sousa Neto, Manoel Damião</creatorcontrib><creatorcontrib>Scariot, Rafaela</creatorcontrib><creatorcontrib>Giovanini, Allan Fernando</creatorcontrib><creatorcontrib>Deliberador, Tatiana Miranda</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of oral biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Auersvald, Caroline Moreira</au><au>Santos, Felipe Rychuv</au><au>Nakano, Mayara Mytie</au><au>Leoni, Graziela Bianchi</au><au>de Sousa Neto, Manoel Damião</au><au>Scariot, Rafaela</au><au>Giovanini, Allan Fernando</au><au>Deliberador, Tatiana Miranda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The local administration of parathyroid hormone encourages the healing of bone defects in the rat calvaria: micro-computed tomography, histological and histomorphometric evaluation</atitle><jtitle>Archives of oral biology</jtitle><addtitle>Arch Oral Biol</addtitle><date>2017-07-01</date><risdate>2017</risdate><volume>79</volume><spage>14</spage><epage>19</epage><pages>14-19</pages><issn>0003-9969</issn><eissn>1879-1506</eissn><abstract>Highlights • The local administration of PTH on bone healing in rat bone defects was evaluated. • Micro-CT, histological and histomorphometric analysis were performed. • At 15 days post-surgery, PTH Group exhibited higher percentage of bone formation. • The results suggest that PTH encouraged the initial bone healing in bone defects.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>28282513</pmid><doi>10.1016/j.archoralbio.2017.02.016</doi><tpages>6</tpages></addata></record> |
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| ispartof | Archives of oral biology, 2017-07, Vol.79, p.14-19 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Advanced Basic Science Animals Bone regeneration Bone Regeneration - drug effects Calvaria Cattle Collagen - pharmacology Dentistry Male Micro-CT Osteogenesis - drug effects Parathyroid hormone Parathyroid Hormone - administration & dosage Parathyroid Hormone - pharmacology Rats Rats, Wistar Skull - diagnostic imaging Skull - drug effects Skull - pathology Skull - surgery Time Factors Wound Healing - drug effects X-Ray Microtomography - methods |
| title | The local administration of parathyroid hormone encourages the healing of bone defects in the rat calvaria: micro-computed tomography, histological and histomorphometric evaluation |
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