Corneal nerve microstructure in Parkinson’s disease

Corneal nerve microstructure in Parkinson’s disease

Highlights • This original research article provides further evidence to support the involvement of the peripheral nervous system in Parkinson’s disease, previously considered to be a central nervous system disorder. • The association between reduced corneal sub-basal nerve density and cognitive dys...

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Veröffentlicht in:Journal of clinical neuroscience 2017-05, Vol.39, p.53-58
Hauptverfasser: Misra, Stuti L, Kersten, Hannah M, Roxburgh, Richard H, Danesh-Meyer, Helen V, McGhee, Charles N.J
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Case-Control Studies
Cornea - innervation
Cornea - pathology
Corneal sub-basal nerves
Female
Humans
In vivo confocal microscopy
Male
Microscopy, Confocal
Middle Aged
Neurology
Parkinson Disease - pathology
Parkinson Disease - physiopathology
Parkinson’s disease
Peripheral neuropathy
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Beschreibung
Zusammenfassung:Highlights • This original research article provides further evidence to support the involvement of the peripheral nervous system in Parkinson’s disease, previously considered to be a central nervous system disorder. • The association between reduced corneal sub-basal nerve density and cognitive dysfunction suggests that this may be due to an inherent neurodegenerative process.
ISSN:0967-5868
1532-2653
DOI:10.1016/j.jocn.2017.02.033