Biologic Response Modifiers: Indications, Implications and Insights

Abstract The field of biologic immune-modulators is currently mushrooming at a dizzying pace. While most of these biologics are tested and approved for one or a few indications, their un-anticipated side effects and their off-label use have contributed significantly to our understanding of basic imm...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2017-05, Vol.139 (5), p.1445-1456
Hauptverfasser:	Davis, Benjamin P., M.D., Ph.D, Ballas, Zuhair K., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Apoptosis Arthritis Arthritis, Rheumatoid - drug therapy Asthma Asthma - drug therapy Autoimmune diseases autoimmunity biologic response modifiers Biological Products - adverse effects Biological Products - pharmacology Biological Products - therapeutic use Biologics Cytokines Cytokines - immunology Cytotoxicity Homeostasis Human subjects Humans immune dysfunction Immune response Immune system immunodeficiency Immunologic Factors - adverse effects Immunologic Factors - pharmacology Immunologic Factors - therapeutic use Immunomodulation infection Inflammatory bowel disease Inflammatory Bowel Diseases - drug therapy Lymphocytes Mutation Rhinitis - drug therapy Side effects Sinusitis - drug therapy Skin Spondylitis, Ankylosing - drug therapy T cell receptors
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