Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

Highlights • Higher CRP-levels were associated with greater depressive symptom severity. • Symptom-specific associations were found among women. • We were able to adjust for important factors, including BMI and smoking.

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Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2017-05, Vol.62, p.344-350
Hauptverfasser: Köhler-Forsberg, Ole, Buttenschøn, Henriette N, Tansey, Katherine E, Maier, Wolfgang, Hauser, Joanna, Dernovsek, Mojca Zvezdana, Henigsberg, Neven, Souery, Daniel, Farmer, Anne, Rietschel, Marcella, McGuffin, Peter, Aitchison, Katherine J, Uher, Rudolf, Mors, Ole
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Allergy and Immunology
Biomarkers - blood
C-Reactive Protein - analysis
Depression - blood
Depression - diagnosis
Depressive Disorder, Major - blood
Depressive Disorder, Major - diagnosis
Female
Humans
Male
Middle Aged
Psychiatric Status Rating Scales
Psychiatry
Risk Factors
Severity of Illness Index
Sex Factors
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Zusammenfassung:Highlights • Higher CRP-levels were associated with greater depressive symptom severity. • Symptom-specific associations were found among women. • We were able to adjust for important factors, including BMI and smoking.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2017.02.020