Salivary gland pleomorphic adenoma in the Netherlands: A nationwide observational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence

Highlights • The standardized incidence rate (ESR) of SGPA is 4.2–4.9 per 100,000 person years. • Women show a higher, increasing incidence and bimodal age distribution of SGPA. • The 20-year recurrence rate was 6.7%. Secondary malignant transformation 0.15%. • Positive or uncertain margins and lowe...

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Veröffentlicht in:Oral oncology 2017-03, Vol.66, p.93-99
Hauptverfasser: Valstar, M.H, de Ridder, M, van den Broek, E.C, Stuiver, M.M, van Dijk, B.A.C, van Velthuysen, M.L.F, Balm, A.J.M, Smeele, L.E
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Sprache:eng
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Zusammenfassung:Highlights • The standardized incidence rate (ESR) of SGPA is 4.2–4.9 per 100,000 person years. • Women show a higher, increasing incidence and bimodal age distribution of SGPA. • The 20-year recurrence rate was 6.7%. Secondary malignant transformation 0.15%. • Positive or uncertain margins and lower age showed a higher odds of recurrence. • Tumors situated in the minor glands had a lower odds of recurrence.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2017.01.004