Blepharochalasis: something to cry about

Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be relate...

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Veröffentlicht in:Journal of cutaneous pathology 2017-03, Vol.44 (3), p.279-282
Hauptverfasser: Browning, Richard J., Sanchez, April T., Mullins, Stephen, Sheehan, Daniel J., Davis, Loretta S.
Format: Artikel
Sprache:eng
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Zusammenfassung:Blepharochalasis is a rare disorder of unknown etiology defined by loose, atrophic periorbital skin following recurrent episodes of eyelid edema. Characteristic histopathology shows complete absence of elastic fibers. The current case progressed after multiple episodes of crying, which may be related to matrix metalloproteinase dysregulation. This case offers further insights into the possible pathogenesis of blepharochalasis, paving the way for more targeted, disease‐modifying therapies.
ISSN:0303-6987
1600-0560
DOI:10.1111/cup.12841