The bone morphogenetic protein system and the regulation of ovarian follicle development in mammals

The bone morphogenetic protein (BMP) family consists of several growth factor proteins that belong to the transforming growth factor-β (TGF-β) superfamily. BMPs bind to type I and type II serine–threonine kinase receptors, and transduce signals through the Smad signalling pathway. BMPs have been ide...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Zygote (Cambridge) 2016-02, Vol.24 (1), p.1-17
Hauptverfasser:	Rossi, Rodrigo O.D.S., Costa, José J.N., Silva, Anderson W.B., Saraiva, Márcia V.A., Van den Hurk, Robert, Silva, José R.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Protein Receptors - genetics Bone Morphogenetic Protein Receptors - metabolism Bone Morphogenetic Proteins - physiology Female Mammals Oogenesis - physiology Ovary - growth & development Ovary - physiology Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The bone morphogenetic protein (BMP) family consists of several growth factor proteins that belong to the transforming growth factor-β (TGF-β) superfamily. BMPs bind to type I and type II serine–threonine kinase receptors, and transduce signals through the Smad signalling pathway. BMPs have been identified in mammalian ovaries, and functional studies have shown that they are involved in the regulation of oogenesis and folliculogenesis. This review summarizes the role of the BMP system during formation, growth and maturation of ovarian follicles in mammals.
ISSN:	0967-1994 1469-8730
DOI:	10.1017/S096719941400077X