Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16α-carbonitrile

Expression of cytochromes P450 3A (CYP3A) has been reported in the lung, but its regulation has received little attention. In the present study, we assessed lung levels of Cyp3a mRNA, protein and activity in control mice and in mice treated with either dexamethasone (DEX), pregnenolone 16 alpha -car...

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Veröffentlicht in:Archives of toxicology 2003-03, Vol.77 (3), p.145-149
Hauptverfasser: HAAG, Muriel, FAUTREL, Alain, GUILLOUZO, André, FROSSARD, Nelly, PONS, Francoise
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Sprache:eng
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