Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis

Breakthrough invasive mold infections (IMIs) that occur during posaconazole or voriconazole prophylaxis are rare complications for which epidemiological data are lacking. This retrospective analysis comparing 24 microbiologically documented breakthrough with 66 nonbreakthrough IMIs shows a shift tow...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2017-06, Vol.64 (11), p.1619-1621
Hauptverfasser:	Lamoth, Frederic, Chung, Shimin J., Damonti, Lauro, Alexander, Barbara D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antifungal agents Antifungal Agents - administration & dosage Antifungal Agents - pharmacology Aspergillosis - epidemiology Aspergillosis - prevention & control Azoles - administration & dosage Azoles - pharmacology BRIEF REPORT Drug Resistance, Fungal Epidemiology Female Fungal infections Fungi - drug effects Fungi - pathogenicity Humans Invasive Fungal Infections - epidemiology Invasive Fungal Infections - microbiology Invasive Fungal Infections - mortality Invasive Fungal Infections - prevention & control Male Microbial Sensitivity Tests Middle Aged Mold Mucormycosis - epidemiology Mucormycosis - prevention & control Multidrug resistance Multidrug resistant organisms Patients Posaconazole Prophylaxis Retrospective Studies Voriconazole
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Breakthrough invasive mold infections (IMIs) that occur during posaconazole or voriconazole prophylaxis are rare complications for which epidemiological data are lacking. This retrospective analysis comparing 24 microbiologically documented breakthrough with 66 nonbreakthrough IMIs shows a shift towards non-Aspergillus molds with a significantly increased proportion of rare multidrug-resistant molds.
ISSN:	1058-4838 1537-6591
DOI:	10.1093/cid/cix130