On-Treatment Analysis of the Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT)

Abstract Background We aimed to determine the efficacy and safety of adding ezetimibe (Ez) to simvastatin (S) in a post-acute coronary syndrome (ACS) population in a prespecified on-treatment analysis. Methods We evaluated 17,706 post-ACS patients from the IMPROVE-IT trial who had low-density lipopr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American heart journal 2016-12, Vol.182, p.89-96
Hauptverfasser:	Blazing, Michael A., MD, Giugliano, Robert P., MD, SM, de Lemos, James A., MD, Cannon, Christopher P., MD, Tonkin, Andrew, MBBS, MD, Ballantyne, Christie M., MD, Lewis, Basil S., MD, Musliner, Thomas A., MD, Tershakovec, Andrew M., MD, MPH, Lokhnygina, Yuliya, PhD, White, Jennifer A., MS, Reist, Craig, PhD, McCagg, Amy, BS, Braunwald, Eugene, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - blood Acute Coronary Syndrome - diagnosis Acute Coronary Syndrome - drug therapy Aged Anticholesteremic Agents - administration & dosage Anticholesteremic Agents - adverse effects Cardiovascular Cardiovascular disease Cholesterol, LDL - blood Dose-Response Relationship, Drug Drug Monitoring - methods Drug Synergism Drug Therapy, Combination - methods Drug Therapy, Combination - statistics & numerical data Ezetimibe - administration & dosage Ezetimibe - adverse effects Female Health risk assessment Humans Low density lipoprotein Male Middle Aged Mortality Simvastatin - administration & dosage Simvastatin - adverse effects Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!