Cutaneous manifestations of graft‐versus‐host disease: role of the dermatologist

Summary Graft‐versus‐host disease (GVHD) is the major complication of hematopoietic stem cell transplantation and is associated with high mortality in severe cases. The skin is one of the major organs affected in both acute and chronic GVHD. This review aims to elucidate the basic characteristics of...

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Veröffentlicht in:	International journal of dermatology 2017-02, Vol.56 (2), p.131-140
Hauptverfasser:	Kavand, Sima, Lehman, Julia S., Hashmi, Shahrukh, Gibson, Lawrence E., el‐Azhary, Rokea A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Calcineurin Inhibitors - therapeutic use Chronic Disease Dermatology Graft vs Host Disease - diagnosis Graft vs Host Disease - etiology Graft vs Host Disease - therapy Graft-versus-host reaction Grafting Graft‐versus‐host disease hematology Hematopoietic Stem Cell Transplantation - adverse effects Humans Immunoglobulins, Intravenous - therapeutic use immunology leukemia lymphoma Organs Patients Photopheresis Physician's Role PUVA Therapy Risk Factors sclerosis Skin Skin Diseases - diagnosis Skin Diseases - etiology Skin Diseases - therapy Stem cell transplantation Steroids - therapeutic use systemic disease Transplantation vacuolar interface dermatitis
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Zusammenfassung:	Summary Graft‐versus‐host disease (GVHD) is the major complication of hematopoietic stem cell transplantation and is associated with high mortality in severe cases. The skin is one of the major organs affected in both acute and chronic GVHD. This review aims to elucidate the basic characteristics of GVHD, and the role and contribution of dermatologists in the care of patients with this condition.
ISSN:	0011-9059 1365-4632
DOI:	10.1111/ijd.13381