Femoral indicator injection for transpulmonary thermodilution using the EV1000/VolumeView registered : do the same criteria apply as for the PiCCO registered ?

Objective: Comparison of global end-diastolic volume index (GEDVI) obtained by femoral and jugular transpulmonary thermodilution (TPTD) indicator injections using the EV1000/VolumnView registered device (Edwards Lifesciences, Irvine, USA). Methods: In an 87-year-old woman with hypovolemic shock and equipped with both jugular and femoral vein access and monitored with the EV1000/VolumeView registered device, we recorded 10 datasets, each comprising duplicate TPTD via femoral access and duplicate TPTD (20 ml cold saline) via jugular access. Results: Mean femoral GEDVI ((674.6 plus or minus 52.3) ml/m super(2)) was significantly higher than jugular GEDVI ((552.3 plus or minus 69.7) ml/m super(2)), with P=0.003. Bland-Altman analysis demonstrated a bias of (+122 plus or minus 61) ml/m super(2), limits of agreement of -16 and +260 ml/m super(2), and a percentage error of 22%. Use of the correction-formula recently suggested for the PiCCO registered device significantly reduced bias and percentage error. Similarly, mean values of parameters derived from GEDVI such as pulmonary vascular permeability index (PVPI; 1.244 plus or minus 0.101 vs. 1.522 plus or minus 0.139; P