Influence of body mass index on revision rates after primary total knee arthroplasty

Purpose Studies demonstrate that revision rates after primary total knee arthroplasty (TKA) tend to be higher in obese patients. However, the existence of a body mass index (BMI) threshold remains unexplored. Methods We conducted a prospective cohort study of 2442 primary TKAs in 2035 patients (69.1...

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Veröffentlicht in:International orthopaedics 2016-04, Vol.40 (4), p.723-729
Hauptverfasser: Zingg, Matthieu, Miozzari, Hermès H., Fritschy, Daniel, Hoffmeyer, Pierre, Lübbeke, Anne
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Sprache:eng
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Zusammenfassung:Purpose Studies demonstrate that revision rates after primary total knee arthroplasty (TKA) tend to be higher in obese patients. However, the existence of a body mass index (BMI) threshold remains unexplored. Methods We conducted a prospective cohort study of 2442 primary TKAs in 2035 patients (69.1 % women; mean age 72 years; mean follow-up 93 months, range 38–203). We evaluated the influence of BMI in five categories on all-cause revision after TKA using incidence rates (IR), hazard ratios (HR), and Kaplan–Meier survival analysis. Adjustment for baseline imbalances was performed using Cox regression analysis. Results Over the study period, 71 revisions occurred. Revision rates were 3.2 cases/1000 patient-years for patients of normal weight, 3.4/1000 for overweight patients and 3.0/1000 for patients classified as obese class I. At BMI ≥ 35, a significant increase in revision was noted. Comparing BMI ≥ 35 vs. < 35, there were 6.4 vs. 3.2 /1000. Crude HR was 2.0 [95 % confidence interval (CI) 1.2–3.3, p  = 0.009], and the adjusted HR was 2.1 (95 % CI 1.2–3.6, p  = 0.008). Conclusion All-cause revision rates after primary TKA doubled in patients with a BMI of 35 but were similar in those with a BMI
ISSN:0341-2695
1432-5195
DOI:10.1007/s00264-015-3031-0