Peri-operative blood-loss after total hip arthroplasty can be significantly reduced with topical application of epsilon-aminocaproic acid

Peri-operative blood-loss after total hip arthroplasty can be significantly reduced with topical application of epsilon-aminocaproic acid

Purpose To evaluate the peri-operative blood loss with the use of epsilon-aminocaproic acid (ε-ACA) in total hip arthroplasty (THA). Methods One hundred sixty patients treated with THA were followed; 5 g ε-ACA diluted in 100 ml normal saline was applied intra-operatively. Eighty patients not receivi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International orthopaedics 2016-10, Vol.40 (10), p.2019-2023
Hauptverfasser: Sucher, Mark G., Giordani, Mauro, Figoni, Andrew, Nedopil, Alexander J.
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Topical
Aged
Aminocaproic Acid - therapeutic use
Antifibrinolytic Agents - therapeutic use
Arthroplasty, Replacement, Hip - adverse effects
Arthroplasty, Replacement, Hip - methods
Blood Loss, Surgical - prevention & control
Blood Transfusion
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Original Paper
Orthopedics
Retrospective Studies
Thromboembolism - etiology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Purpose To evaluate the peri-operative blood loss with the use of epsilon-aminocaproic acid (ε-ACA) in total hip arthroplasty (THA). Methods One hundred sixty patients treated with THA were followed; 5 g ε-ACA diluted in 100 ml normal saline was applied intra-operatively. Eighty patients not receiving ε-ACA (non ε-ACA group) and eighty patients receiving ε-ACA (ε-ACA group) were compared regarding blood loss, need of transfusion, and thrombo-embolic complications. Results Blood loss (mean ± SD) for the non ε-ACA group was 1678 ± 515 ml and for the ε-ACA group 1403 ± 417 ml (p 
ISSN:0341-2695
1432-5195
DOI:10.1007/s00264-015-3103-1