Bacterial cell cycle classification. Application to DNA synthesis and DNA content at any cell age

A proposal is presented for classifying bacterial cell cycles into twelve discrete groups. This classification translates the three temporal parameters that define a cell cycle into numbers that facilitate an algorithmic approach to analyse the replication state of a single bacterium and of a bacter...

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Veröffentlicht in:Journal of theoretical biology 2017-04, Vol.419, p.8-12
1. Verfasser: Jiménez-Sánchez, Alfonso
Format: Artikel
Sprache:eng
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Zusammenfassung:A proposal is presented for classifying bacterial cell cycles into twelve discrete groups. This classification translates the three temporal parameters that define a cell cycle into numbers that facilitate an algorithmic approach to analyse the replication state of a single bacterium and of a bacterial population during steady-state of exponential growth. The classification and its implementation offer easy ways to obtain the rate of DNA synthesis and the amount of DNA per cell at any age in batch cultures.
ISSN:0022-5193
1095-8541
DOI:10.1016/j.jtbi.2017.01.045