The use of intravenous tPA for the treatment of severe frostbite

Highlights • Intravenous tPA has a role in the treatment of severe frostbite. • Consider anti-platelet therapy for patients in whom Coumadin is contra-indicated. • Protocol for IV tPA and anti-platelet therapy from one institution is reviewed.

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Bibliographische Detailangaben
Veröffentlicht in:	Burns 2017-08, Vol.43 (5), p.1088-1096
Hauptverfasser:	Jones, Larry M, Coffey, Rebecca A, Natwa, Mona P, Bailey, J. Kevin
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Adult Aged Anti-platelet therapy Anticoagulants - therapeutic use Critical Care Female Fibrinolytic Agents - administration & dosage Frostbite Frostbite - drug therapy Humans Intravenous tPA Male Middle Aged Platelet Aggregation Inhibitors - therapeutic use Thrombolytic Therapy - methods Tissue Plasminogen Activator - administration & dosage Warfarin - therapeutic use Young Adult
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Beschreibung
Zusammenfassung:	Highlights • Intravenous tPA has a role in the treatment of severe frostbite. • Consider anti-platelet therapy for patients in whom Coumadin is contra-indicated. • Protocol for IV tPA and anti-platelet therapy from one institution is reviewed.
ISSN:	0305-4179 1879-1409
DOI:	10.1016/j.burns.2017.01.013